# Antidiuretic Hormone --- **Antidiuretic hormone** or **ADH** (sometimes called **vasopressin**) is a [[hormone]] that is produced by the [[hypothalamus]] and then stored and secreted by the [[pituitary gland|posterior pituitary]] gland when the body is getting dehydrated as a method of retaining water by reducing the amount of [[urine]]. ADH is released in response to high serum [[osmosis|osmolarity]], as well as baroreceptors in the heart, stress, inflammatory signals and some medications. ADH primarily effects the [[kidneys]] by inserting [[channel proteins|aquaporins]] onto the collecting ducts, and thus [[tubular reabsorption|reabsorbing]] a bunch of water. It also has a secondary effect of stimulating the [[hypothalamus|thirst center]] of the hypothalamus. ADH is sometimes called **vasopressin**, because it can act as a [[blood vessels#Vasodilation & Vasoconstriction|vasoconstrictor]] especially when released in large amounts. This is typically noticeable if someone is injured. ## Problems with Antidiuretic Hormone - [[SIADH]] is an overproduction of ADH - [[diabetes insipidus]] is an underproduction of ADH ___